Thinking About Predictive Genetic Testing for Dilated Cardiomyopathy (DCM)?

What is Predictive Genetic Testing?

Predictive genetic testing helps determine if you inherited a gene change (pathogenic or likely pathogenic variant) known to cause Dilated Cardiomyopathy (DCM) in your family.

Why Consider Predictive Genetic Testing?

Early Detection and Prevention:

• If you have the familial genetic variant, your doctors can provide early monitoring and preventive care.

• Early detection means early treatment, reducing the risk of serious heart issues.

Personalized Medical Care:

• Knowing your genetic risk helps doctors tailor your heart care specifically to you.

• Certain gene changes (like LMNA, FLNC, DSP, DES, RBM20, PLN) may require closer monitoring or preventive measures such as an ICD or pacemaker.

Family and Future Planning:

• Genetic testing helps clarify your risk of passing DCM to your children.

• Options like preimplantation genetic testing (PGT) can be discussed with a genetic counsellor to reduce the chance of passing the condition to future children.

What Do My Results Mean?

Positive (familial gene variant found):

• You carry the gene change and have an increased risk of developing DCM.

• Regular heart check-ups and preventive care are important.

Negative (familial gene variant absent):

• You did not inherit the specific familial gene variant.

• There is no risk of you passing this gene to your children.

• Your risk of developing DCM is the same as the general population.

Your Rights in Canada:

• Genetic test results cannot be used against you in employment, insurance, or housing.

• You must give written consent before your results can be shared.

• Violating these rights can lead to serious legal consequences, including fines or imprisonment.

Bottom Line:

Predictive genetic testing empowers you to make informed health and family decisions, knowing your genetic rights are protected in Canada.